Kannan

RAGHURAMAN KANNAN
Assistant Professor
Office Address:		301 Business Loop 70 West/Room 103 Department of Radiology University of Missouri Columbia , MO 65212
Phone:		(573) 882-5676
Fax:		(573) 884-5679
Email:		KannanR@health.missouri.edu

Education:
1999	Ph.D	Chemistry, Indian Institute of Science, Banglore
1993	M.S	Chemistry, Indian Institute of Technology, Chennai
Professional Experience:
2005		Assistant Professor, Department of Radiology/Chemistry, University of Missouri – Columbia, Columbia, MO
2003		Assistant Research Professor, Department of Radiology/Chemistry, University of Missouri – Columbia, Columbia, MO
2000 - 2003		Post-Doctoral Fellow, Department of Radiology/Chemistry, University of Missouri – Columbia, Columbia, MO
Research Interests:
• Application of Nanoparticles in the field of medicine • Design and development of novel bifunctional chelate agents and their transition metal complexes, and investigate their applications for both catalysis and biomedicine. • Chemical and biomedical aspects of non-linear optical materials. • Development of new generation of chemotherapeutic agents. • Organometallic chemistry of specific transition metals with new chiral bisphosphanes and functionalized phosphanes-synthetic and catalytic aspects. • Structure of Water and Water-Methanol Clusters
Recent Publications and Patent Abstracts:
Kannan, Raghuraman; Rahing, Valerie; Cutler, Cathy; Pandrapragada, Ravi; Katti, Kavita K.; Kattumuri, Vijaya; Robertson, J. David; Casteel, Stan J.; Jurisson, Silvia; Smith, Charles; Boote, Evan; Katti, Kattesh V. Nanocompatible Chemistry toward Fabrication of Target-Specific Gold Nanoparticles. Journal of the American Chemical Society (2006), 128(35), 11342-11343. Kattumuri, Vijaya; Katti, Kavita; Bhaskaran, Sharanya; Boote, Evan J.; Casteel, Stan W.; Fent, Genevieve M.; Robertson, David J.; Chandrasekhar, Meera; Kannan Raghuraman; Katti, Kattesh V. Gum Arabic as a phytochemical construct for the stabilization of gold nanoparticles: in vivo pharmacokinetics and X-ray-contrast-imaging studies. Small (2007), 3(2), 333-341. Raghuraman, Kannan; Katti, Kavita K.; Barbour, Leonard J.; Pillarsetty, Nagavarakishore; Barnes, Charles L.; Katti, Kattesh V. Characterization of Supramolecular (H20)18 Water Morphology and Water-Methanol (H20)15(CH3OH)3 Clusters in a Novel Phosphorus Functionalized Trimeric Amino Acid Host. Journal of the American Chemical Society (2003), 125(23), 6955-6961. Raghuraman, Kannan; Katti, Kattesh K.; Katti, Kavita K.; White, Henry W; Cutler, Cathy S. Methods and articles for gold nanoparticle production. PCT Int. Appl. (2007), 30pp. CODEN:PIXXD2 WO 2007027978 A2 20070308 CAN 146:3+22+2 AN 2001:259624 CAPLUS Raghuraman, Kannan; Katti, Kattesh V. Methods for producing silver nanoparticles. U.S. Pat. Appl. Publ. (2006), 6pp. CODEN: USXXCO US 2006045916 A1 20060302 CAN 114:260825 AN 2006:192175 CAPLUS Smith, C. Jeffrey; Sieckman, Gary L; Woen, Nellie K.; Hayes, Donald L.; Mazuru, Dana g.; Kannan Raghuraman; Volkert, Wynn A.; Hoffman, Timothy J. Radiochemical Investigations of gastrin-releasing Peptide Receptor-specific [ 99m Tc(X)(CO) 3 – Dpr-Ser-Ser-Ser-Gln-Trp-Ala-Val-Gly-His-Leu-Met-(NH 2)] in PC-3, Tumor-bearing, Rodent Models: Syntheses, Radiolabeling, and in Vitro/in Vivo Studies where Dpr = 2,3-Diaminopropionic acid and X= H2) or P(CH2OH)3. Cancer Research (2003), 63, 4082-4088. Kothari, K.K.; Raghuraman, K.; Pillarsetty, N.K.; Hoffman, T.J.; Owen, N.K.; Katti, K.V.; Volkert, W.A. Syntheses, in vitro and in vivo characterization of a 99m Tc(I)-tricarbonyl-benzylamino-dihydroxymethayl phosphine (NP 2 ) chelate. Applied Radiation and Isotopes (2003), 58, 543-549. Raghuraman, K.; Pillarsetty, N.; Volkert, W.A.; Barnes, C.; Jurisson, S.; and Katti, K.V. Exceptional Kinetic Propensity of Hydroxymethyl Phosphanes Toward Rh(III) Stabilization in Water. J. Am. Chem. Soc. (2002), 124, 7276-7277. Katti, K.V.; Raghuraman, K.; Pillarsetty, N.; Karra, S.R.; Rulotty, R.J.; Chartier, M.A.; and Langhoff, C.A. First Examples of Azaphosphanes as Efficient Electron Donors in the Chemical Archictecture of Thermally Stable New Nonlinear Optical Materials. Chemistry of Materials (2002), 14, 2436-2438. Katti, K.V.; Raghuraman, K.; Pillarsett, N.; Volkert, W.A.; Jurisson, S.S.; and Hoffman, T.J. Novel Tridentate Water-Soluble Phosphane Based Ligands for Stabilizing Tc(I)/Re(I) Carbonyls for Radiopharmaceutical Applications. Technetium, Rhenium, and Other Metals in Chemistry and Nuclear Medicine. M. Nicolini, U. Mazzi Eds., SGE Editoriali, Padova, Italy (2002), 6, 69. Raghuraman, K.; Pillarsetty, N.; Prabhu, K.R.; Katti, K.V. Novel Green Chemistry in the Phosphonate Assisted Catalytic Hydrogenation of Olefins. Phosphorus Sulfur and Silicon (2002), 177, 1951. Raghuraman, K.; Krishnamurthy, S.S.; Nethaji, M. Half-sandwich Cyclopentadienyl Ruthenium Complexes of Achiral and Chiral Diphosphazanes. J. Chem. Soc., Dalton . Trans., (2002), 22, 4289-4295.